1. 2005;8;297-308The Pharmacology of Sedation
   A Focused Review
   James D. Colson, MD.

Sedation is commonly provided for patients undergoing interventional pain management procedures. Although many pain management interventionalists have trained in anesthesiology, the use of sedatives, analgesics and hypnotics, as well as monitoring techniques, may vary considerably between practices.

This review provides an update on recent advances in the pharmacology of drugs commonly used for sedation, anxiolysis and analgesia. The information should also be useful for non-anesthesiologists who provide sedation for their patients. In addition to providing the right drug for the procedure, patient monitoring must be appropriate for the patient and the clinical circumstances. Undertaking a sedation analgesic course of therapy in support of an interventional procedure will require that patients are monitored appropriately during the course of treatment. Guidelines for monitoring patients during sedation are available.

Keywords: sedation, anxiolysis, opioids, barbiturates, benzodiazepines, ketamine, etomidate, propfol, sedation for interventional pain management.